Namespaces

Variants
Actions
Personal tools

MACS

From UABgrid Documentation

(Difference between revisions)
Jump to: navigation, search
(added category software)
(added category bioinformatics)
 
Line 13: Line 13:
  
  
[[Category:Software]]
+
[[Category:Software]][[Category:Bioinformatics]]

Latest revision as of 10:16, 4 April 2012

This page is a Generic stub.

You can help by expanding this page..


MACS empirically models the length of the sequenced ChIP fragments, which tends to be shorter than sonication or library construction size estimates, and uses it to improve the spatial resolution of predicted binding sites. MACS also uses a dynamic Poisson distribution to effectively capture local biases in the genome sequence, allowing for more sensitive and robust prediction. MACS compares favorably to existing ChIP-Seq peak-finding algorithms, is publicly available open source, and can be used for ChIP-Seq with or without control samples.

Project website: http://liulab.dfci.harvard.edu/MACS/

[edit] Load SGE module

To load MACS into your environment, use the following module command:

module load macs/macs